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Two expert listeners rated severity of hypernasality and voice impairment in sentences produced by individuals with ALS ( n = 27). This report explores (a) the extent to which acoustic measures are affected by concurrent perceptually identified hypernasality and voice impairment due to ALS and (b) candidate acoustic measures of early indicators of hypernasality and voice impairment in the presence of multisystem involvement in individuals with ALS. Existing acoustic measures have been developed to primarily target either hypernasality or voice impairment, and the effects of co-occurring hypernasality-voice problems on these measures are unknown. Hypernasality and atypical voice characteristics are common features of dysarthric speech due to amyotrophic lateral sclerosis (ALS). The results of this study support the growing body of literature documenting the significant value of cepstral and other spectral-based acoustic measures to the clinical evaluation and management processes. In a sample of dysphonic speakers (hypofunctional etiologies) versus typical speakers, spectral/cepstral measures of CPP and L/H ratio were able to differentiate these groups from one another in both vowel prolongation and continuous speech contexts with high sensitivity and specificity. In differentiating dysphonic individuals with a hypofunctional etiology from nondysphonic individuals, receiver operating characteristic (ROC) analyses demonstrated (a) high sensitivity and high specificity for the CPP in the sustained vowel condition and (b) high sensitivity and moderate specificity for the CPP in the speech condition.
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Measures of cepstral peak prominence (CPP) and low-high spectral ratio (L/H ratio) were significantly different between groups in both speaking conditions the standard deviation of the CPP was significantly different between groups in continuous speech only.
Cepstral voices free download software#
Recorded voices were analyzed with custom software that calculated 4 spectral/cepstral measures.
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Thirty-two age- and gender-matched individuals (16 participants with dysphonia and 16 controls) were recorded reading a standard passage (The Rainbow Passage Fairbanks, 1960) and sustaining the vowel /α/. In this study, the authors evaluated the diagnostic value of spectral/cepstral measures to differentiate dysphonic from nondysphonic voices using sustained vowels and continuous speech samples.